Figure 7
From: Identification and characterization of Dicer1e, a Dicer1 protein variant, in oral cancer cells
Knockdown of Dicer1e enhances chemosensitivity to cisplatin in oral cancer cells. The OSCC cell line SCC-25 was transfected with either control non-targeting siRNA (siNT) or siRNA targeting Dicer1e (siDicer1e). 24 hours post-transfection, 1.8 μM of cisplatin (CDDP) was added and 48 hours later the cell viability was assessed. Data are mean ± SEM of four independent experiments, where *P < 0.05 and **P < 0.01 compared to cisplatin and siDicer1e alone treated cells (Student’s t test).