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Figure 6 | Molecular Cancer

Figure 6

From: Transducin β-like 1 X-linked receptor 1 suppresses cisplatin sensitivity in Nasopharyngeal Carcinoma via activation of NF-κB pathway

Figure 6

TBL1XR1 activates NF-κB signaling pathway. (A) Luciferase-reporter NF-κB activity in indicated cells. (B) Real-time PCR analysis indicating an apparent overlap between NF-κB-dependent gene expression and TBL1XR1-regulated gene expression. The pseudo color represents the intensity scale of TBL1XR1 vs Vector, or TBL1XR1 short hairpin RNA vs RNAi-vector, generated by a log2 transformation. (C) Analysis of expression and correlation of TBL1XR1 with Bcl-2, Bcl-xl, c-FLIP and IκB mRNA expression, as well as NF-κB activity in 10 freshly collected NPC biopsies.

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Molecular Cancer

ISSN: 1476-4598