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Figure 5 | Molecular Cancer

Figure 5

From: Clinical relevance and therapeutic potential of angiopoietin-like protein 4 in hepatocellular carcinoma

Figure 5

ANGPTL4 promoted apoptosis and suppressed angiogenesis of HCC. (A) TUNEL assay on liver tumor tissues. (B) Determination of microvessel density (MVD) of liver tumor tissues by immunohistochemical staining using anti-CD34 antibody. (C) Western blot analysis of VEGF, phosphor-Raf, Phospho-MEK, Phospho-Erk, ANGPTL4 and beta-actin proteins in liver tumor tissues in Ad-ANGPTL4 and Ad-Luc groups. The average protein expression between Ad-ANGPTL4 and Ad-Luc group was quantified and summarized in the lower panel figures. (D) Western blot analysis of proteins in MHCC97L cells after treating with rNGPTL4 protein. *, P < 0.05.

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