Skip to main content

Table 1 CXCR7 and CXCR4 mRNA level relative to PPIA (FD)

From: The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation

Cell line ER PR HER2 Tumor type Classification CXCR7 CXCR4
MCF10A* - - - F Basal B 0.07 0.03
MCF12A* - - - F Basal B 0.01 0.47
MCF7 + + - IDC Luminal 0.53 0.03
T47D + + - IDC Luminal 0.04 0.06
BT474 + + + IDC Luminal 0.94 0.20
SKBR3 - - + AC Luminal 0.00 0.19
MDAMB231 - - - AC Basal B 0.04 0.19
HCC202 - - + Duc Ca Luminal 0.15 0.07
HCC 1569 - - + MC Basal 0.02 0.03
HCC 1954 - - + Duc Ca Basal A 0.03 0.03
  1. CXCR7 and CXCR4 mRNA expression relative to PPIA expression was analyzed by q-PCR. The cell line classification based on estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) status was also included in this table as previously described in the literature[21].
  2. *immortalized normal epithelial cells.
  3. F = Fibrocystic disease.
  4. IDC = invasive ductal carcinoma.
  5. AC = adenocarcinoma.
  6. MC = metastatic carcinoma.
  7. Duc Ca = Ductal carcinoma.