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Figure 7 | Molecular Cancer

Figure 7

From: Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKβ/NF-κB signaling pathway in lung cancer cells

Figure 7

CS-6 inhibited tumor growth in lung cancer mouse models. An orthotopic mouse model of human NSCLC A549 was used to evaluate the effect of CS-6. Tumor volumes (A) and total weights (B) were measured. (C) H&E staining. (D). Immunohistochemical analysis of COX-2 and p-p65 protein expression in tumor samples. Neutral formalin fixed tumor samples were prepared from animals and analyzed by immunohistochemical staining with rabbit anti-rabbit second antibody using the Vectastain Elite ABC kit, and examined under a microscope.

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