Figure 5From: Cholesterol depletion by methyl-β-cyclodextrin augments tamoxifen induced cell death by enhancing its uptake in melanomaDetection of tamoxifen in tumor of mice administered with tamoxifen and MCD. (A) Extracted ion chromatogram (XIC) of selected fragment ion (m/z 72.0808) of tamoxifen. (B) MS/MS fragmentation pattern of tamoxifen. (C) Quantitation of tamoxifen by area under curve of tumor. (D and E) Quantitation of tamoxifen by area under curve of liver and kidney, respectively. Values of tumors are represented as mean ± SD (n = 3). For liver and kidney values are mean of two samples.Back to article page