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Figure 6 | Molecular Cancer

Figure 6

From: Twist1 expression induced by sunitinib accelerates tumor cell vasculogenic mimicry by increasing the population of CD133+ cells in triple-negative breast cancer

Figure 6

Effects of Twist1 levels on CD133 expression and VM-like channel formation by breast cancer cells. MDA-MB-231 cells did not form VM-like channels when Twist1 expression was inhibited under conditions of normoxia, hypoxia, and reoxygenation, and CD133 expression was inhibited as well. When Twist1 expression was up-regulated, MCF-7 cells formed VM channels under conditions of normoxia and reoxygenation. Moreover, the tumor cells that lined the VM channels were CD133+. The error bar = 100 μm, and the error bar indicates the SD.

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Molecular Cancer

ISSN: 1476-4598