Figure 2
From: TopBP1 and Claspin contribute to the radioresistance of lung cancer brain metastases
Expression microarray analysis of two induced radioresistant cell lines. (A) Venn diagram shows the number of genes with expression change by radiotherapy in PC14PE6 or H460 cells from xenografted models. Genes were selected using a filter criterion of at least 2-fold change compare to no radiotherapy control with p < 0.05. (B-C) Genes with altered expression in radioresistant H460-10Gy and PC14PE6-20Gy are categorized into 15 functional groups based on the gene ontology. The gene numbers are displayed in graphs.