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Figure 2 | Molecular Cancer

Figure 2

From: The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation

Figure 2

DEK binds to highly expressed genes. Frequency of DEK binding to genes, based on their expression. Absolute expression levels in the U937 cell line for all genes in the genome were determined by Cap Analysis of Gene Expression (CAGE). The genes were then ordered based on their expression and grouped into bins of one thousand genes, with the thousand genes with the highest expression in the leftmost column and the ones with the lowest expression in the rightmost column. For each group, we calculated the proportion of the genes that were found to be bound by DEK, showing that DEK binds most commonly to highly transcribed genes (A). Distribution of DEK peaks relative to the transcription start sites of genes with no (B), low (C), intermediate (D) and high (E) expression.

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