Skip to main content

Table 1 DEK binds to genes involved in multiple cellular functions

From: The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation

Gene ontology term

Fold enrichment

P value

Nucleosome assembly

5.96

2.7 × 10−6

mRNA metabolic process

2.95

1.8 × 10−8

RNA splicing

2.82

5.3 × 10−3

Ubiquitin-dependent protein catabolic process

2.59

4.9 × 10−3

Cellular macromolecular complex assembly

2.58

5.0 × 10−5

Viral process

2.34

7.2 × 10−4

Interspecies interaction between organisms

2.20

2.8 × 10−3

Protein complex biogenesis

2.16

7.9 × 10−5

Cell cycle

1.84

4.7 × 10−4

Cellular catabolic process

1.70

2.5 × 10−3

Gene expression

1.41

5.0 × 10−4

  1. Gene ontology analysis of the DEK-bound genes, showing enrichment in many categories that are central for cancer biology.