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Figure 3 | Molecular Cancer

Figure 3

From: OncomiR-196 promotes an invasive phenotype in oral cancer through the NME4-JNK-TIMP1-MMP signaling pathway

Figure 3

NME4 suppressed the effect of miR-196s on cell migration and invasion. (A) Verification of the expression status of miR-196 s and NME4 after transfection of the miR-196 overexpression or NME4 plasmids. After the transfection of miR-196 and/or NME4 plasmids into OECM1 cells, cell invasion (B) and migration (C) were examined as described in the Methods section. The empty vectors (pcDNA for miR-196 and pCIneo for NME4) were added if necessary to make total DNA amount being equally used in all experiments. (*p < 0.05, **p < 0.01, ***p < 0.005, t-test).

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