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Table 1 Association among clinicopathological variables and THBS2 expression and overall survival of gastric cancer patients

From: Down regulation of Thrombospondin2 predicts poor prognosis in patients with gastric cancer

Variables Negative Positive Total No. P valuea Overall survival OS
Log-Rank Pb HR(95% CI)
  No.(%) No.(%)     
Age (y)     0.112 0.743  
<61 24(38.1) 39(61.9) 63    1(reference)
≥61 35(53.0) 31(47.0) 66    1.09(0.67-1.77)
Gender     0.831 0.405  
Male 47(46.5) 54(53.5) 101    1(reference)
Female 12(42.9) 16(57.1) 28    0.76(0.40-1.45)
Histological grade     0.005 0.011  
Well and moderate 24(33.8) 47(66.2) 71    1(reference)
Poor and other 35(60.3) 23(39.7) 58    1.89(1.16-3.09)
Tumor location     0.419 0.204  
Upper 27(40.3) 40(59.7) 67    1(reference)
Middle 15(53.6) 13(46.4) 28    1.66(0.86-3.18)
Lower 17(50.0) 17(50.0) 34    1.90(0.90-4.01)
Depth of invasion     0.271 0.001  
T1-T2 9(34.6) 17(65.4) 26    1(reference)
T3-T4 50(48.5) 53(51.5) 103    11.60(2.83-47.45)
Lymph node metastasis     0.454 <0.001  
Absent 17(40.5) 25(59.5) 42    1(reference)
Present 42(48.3) 45(51.7) 87    5.16(2.46-10.84)
TNM stage     0.283 <0.001  
I-II 21(39.6) 32(60.4) 53    1(reference)
III-IV 38(50.0) 38(50.0) 76    7.14(3.52-14.49)
  1. Bold value is statistically significant at P < 0.05, HR hazard ratio.
  2. a, P value of clinicopathological variables and THBS2 expression.
  3. b, P value of association between clinicopathological variables and overall survival of gastric cancer patients.