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Figure 5 | Molecular Cancer

Figure 5

From: miR-193a-3p regulates the multi-drug resistance of bladder cancer by targeting the LOXL4 gene and the Oxidative Stress pathway

Figure 5

The effects of the forced reversal of both miR-193a-3p and LOXL4 levels on the activity of the signaling pathways in 5637 versus H-bc cells. A, The relative activities (in mean ± S.D) of five indicated pathways in 5637 versus H-bc cells. B, The relative pathway activities in the LOXL4 siRNA or miR-193a-3p mimic (3 PM) versus the NC transfected 5637 cells. C, The relative pathway activities in the miR-193a-3p antagomiR (3PA) versus the NC transfected H-bc cells. D, The level of the OS pathway related mRNAs in 5637 and H-bc cells. E, The level of the OS pathway related mRNAs in the miR-193a-3p mimic or siRNA versus the NC transfected 5637 cell. F, The level of the OS pathway related mRNA s in the miR-193a-3p antagomiR versus the NC transfected H-bc cells. (*, p <0.05; **,P < 0.01).

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Molecular Cancer

ISSN: 1476-4598