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Figure 1 | Molecular Cancer

Figure 1

From: OvMark: a user-friendly system for the identification of prognostic biomarkers in publically available ovarian cancer gene expression datasets

Figure 1

Prognostic role of the BRCA2, PRL and CDKN1B in ovarian cancer. In each plot black denotes high expression of the marker(s) and grey denotes low expression. (a) Kaplan-Meier estimates of survival, demonstrating high expression of BRCA2 is associated with poor DFS in ovarian cancer (n = 996, HR = 1.38, p = 1.21 x 10−5). (b) Kaplan-Meier estimate of survival, demonstrating that high expression of BRCA2 and PRL in combination has a greater affect on DFS than expression of either gene alone (n = 996, HR = 1.43, p = 4.71 x 10−4). (c) Combining BRCA2, PRL and CDKN1B increases the HR for DFS further i.e. grouping samples with high expression of all three genes versus the rest (HR = 1.70, p-value = 3.09 x 10−4, n = 996).

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Molecular Cancer

ISSN: 1476-4598