Figure 4From: MCRS1 overexpression, which is specifically inhibited by miR-129*, promotes the epithelial-mesenchymal transition and metastasis in non-small cell lung cancerDifferentially expressed genes related to EMT process after MCRS1 silencing. (a) A mRNA microarray analysis of the expression changes of genes related to EMT in EPLC-32 M1 cells following stable MCRS1 knockdown. +, up-regulation; -, down-regulation. (b, c) qRT-PCR validation of differentially expressed genes with and without MCRS1 knockdown in EPLC-32 M1 and NCI-H292 cells. Luc: cells without MCRS1 silencing; Msh3: cells with stable MCRS1 silencing. The results were analyzed by student’s t-test (P <0.05).Back to article page