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Figure 2 | Molecular Cancer

Figure 2

From: Nedd4-1 is an exceptional prognostic biomarker for gastric cardia adenocarcinoma and functionally associated with metastasis

Figure 2

Nedd4-1 is overexpressed in GCA and the overexpression is tightly negatively correlated with cumulative survival of GCA patients. A, Overexpression of Nedd4-1 in GCA tumor tissue is significantly higher than in their adjacent normal gastric cardia tissue. The average scores and standard deviations of IHC staining of Nedd4-1 in both GCA tumors (T) and their adjacent normal tissue (N) are shown in the figure. B, IHC staining of Nedd4-1 in GCA tumor samples. C, Kaplan-Meier survival curve of Nedd4-1 positive and negative GCA patients in TNM stages I-III. The Chi-square and p values from Mantel-Cox test and the mean survival for Nedd4-1 negative and positive GCA of TNM stages I-III are shown in the figure. D. Kaplan-Meier survival curve of Nedd4-1 positive and negative GCA patients in each of TNM stages. The p value was calculated from Mantel-Cox test.

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