Table 1 Opposite effects of As 2 O 3 or Calcium ionophore A23187 on a panel of leukemic T-cell lines
As2O3(2 μM*) | Calcium ionophore A23187 (100 nM) | |||||||
|---|---|---|---|---|---|---|---|---|
T-cell lines | B220 upregulation** | CD69 upregulation** | HSP70 upregulation** | Cell death*** | B220 upregulation** | CD69 upregulation** | HSP70 upregulation** | Cell death*** |
EL-4 | 63 | No | 35 | 70 | 7 | Yes | no | 1 |
BW5147 | 30 | No | 20 | 39 | 19 | Yes | no | 25 |
Jurkat clone E6-1 | 22 | No | 10 | 12 | 30 | Yes | no | 28 |
HPB-ALL | 10 | No | 3 | 5 | 80 | Yes | no | 75 |
L1210 | Constitutive expression | No | 5 | 10 | Constitutive expression | Yes | no | 55 |