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Figure 4 | Molecular Cancer

Figure 4

From: Comprehensive analysis of microRNA-regulated protein interaction network reveals the tumor suppressive role of microRNA-149 in human hepatocellular carcinoma via targeting AKT-mTOR pathway

Figure 4

Reverse correlation between miR-149 and AKT1 mRNA expression in human HCC tissues and cells. (A and B) Relative expression of miR-149 and AKT1 mRNA in 130 self-pairs of HCC and adjacent nonneoplastic liver tissues; (C) Spearman Correlation analysis clearly showed a negative correlation between miR-149 and AKT1 mRNA expression in HCC tissues (rs = -0.639, P < 0.001); (D) Spearman Correlation analysis clearly showed a negative correlation between miR-149 and AKT1 protein expression in HCC tissues (rs = -0.716, P < 0.001); (E and F) Relative expression of miR-149 and AKT1 mRNA HCC (HepG2) and normal liver (HL-7702) cells.

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Molecular Cancer

ISSN: 1476-4598