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Table 1 Association of miR-149 expression with clinicopathologic features of 130 hepatocellular carcinoma patients

From: Comprehensive analysis of microRNA-regulated protein interaction network reveals the tumor suppressive role of microRNA-149 in human hepatocellular carcinoma via targeting AKT-mTOR pathway

Clinicopathologic features

Case

miR-149-low (n, %)

P

Age (years)

   

≤50

72

38 (52.78)

NS

>50

58

32 (55.17)

Gender

   

Male

96

50 (52.08)

NS

Female

34

20 (58.82)

Serum AFP

   

Positive

72

42 (58.33)

NS

Negative

58

28 (48.28)

Tumor stage

   

T1

23

6 (26.09)

0.01

T2

40

15 (37.50)

T3

52

34 (65.38)

T4

15

15 (100.00)

Tumor grade

   

G1

31

16 (51.61)

NS

G2

76

39 (51.32)

G3

23

15 (65.22)

Growth pattern

   

Trabecular

101

53 (52.48)

NS

Nontrabecular

29

17 (58.62)

Cirrhosis

   

Yes

86

45 (52.33)

NS

No

44

25 (56.82)

Underlying liver disease

   

Alcoholic

25

13 (52.00)

NS

Hepatitis B

49

28 (57.14)

Hepatitis C

35

17 (48.57)

Unknown

21

12 (57.14)

  1. Note: ‘NS’ refers to the differences among groups have no statistical significance.