Figure 3
From: Exosome-mediated transfer of miR-10b promotes cell invasion in breast cancer
Regulation of exosomal miR-10b secretin by ceramide biosynthesis pathway. A, Detection of miR-10b from conditioned medium of MCF-7 cells stably expressing smpd3 and vector control by qRT-PCR. B, Detection of miR-10b from conditioned medium of MDA-MB-231 cells stably expressing smpd3 and vector control by qRT-PCR. C, Secretion of miR-10b is enhanced by the treatment with ceramide in MDA-MB-231 cells. D, Suppression of miR-10b secretion by ceramide biosynthesis inhibitor (GW4869) in MDA-MB-231 cells.