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Figure 1 | Molecular Cancer

Figure 1

From: Developing ovarian cancer stem cell models: laying the pipeline from discovery to clinical intervention

Figure 1

The defining properties stem cells (SC) and cancer stem cells (CSCs). SCs and CSCs can both be defined and validated via three properties. Self-renewal: (C)SCs can divide in a potency preserving fashion, producing two daughter stem cells. Differentiation: When necessary, (C)SCs can differentiate to produce daughter cells of reduced potency. Tissuegenesis: (C)SCs can derive the multiple cell types needed to form their given tissue. In the case of CSCs this is referred to as tumorigenesis (‘malignant tissuegenesis’).

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Molecular Cancer

ISSN: 1476-4598