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Figure 2 | Molecular Cancer

Figure 2

From: Developing ovarian cancer stem cell models: laying the pipeline from discovery to clinical intervention

Figure 2

The undifferentiated stem cell (SC) state is regulated by multiple factors in the stem cell niche. Studies of the SC niche have shown that multiple factors regulate (C)SC activity. The most prominent factors range from chemokine/cytokine signaling and metabolite gradients to basement membrane and stromal cell interactions. Together, these factors regulate the undifferentiated state of SCs and CSCs.

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Molecular Cancer

ISSN: 1476-4598