Figure 5
From: RNAi-mediated silencing of MLL-AF9 reveals leukemia-associated downstream targets and processes
Strategy to prioritize candidate genes concerning mediation of MLL-AF9 leukemogenic effects. Four approaches (second line) were used to select 70 genes from the set of 425 differentially expressed genes after MLL-AF9 knockdown in THP1 cells. Each gene’s likelihood to play a role in leukemogenesis was rated via a structured rating strategy based on data obtained through a literature search.