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Figure 3 | Molecular Cancer

Figure 3

From: Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia

Figure 3

Hypoxic regulation of microRNAs clustered to MIR27A and MIR30D . QPCR was used to assess the expression of both 5p and 3p arms of two microRNA clusters that are within 50 kb of a HIF-binding site: hsa-miR-27a, hsa-miR-23a and hsa-miR-24-2 (A) and hsa-miR-30d and hsa-miR-30b (B). Fold-changes (in linear scale) obtained for each microRNA at each time point relative to normoxia control are represented in boxplots (*significant fold-change compared to normoxia after ANOVA followed by pairwise t-test, adj.p-val ≤ 0.05).

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