Skip to main content
Figure 6 | Molecular Cancer

Figure 6

From: Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia

Figure 6

Hypoxia regulates genes involved in microRNA processing pathway in a HIF-dependent manner. QPCR was performed to monitor the expression of genes involved in the microRNA processing pathway. Hypoxia MCF-7 time course and 2 sets of HIF-1α and HIF-2α siRNA in MCF-7 were analysed. Fold-changes (in linear scale) obtained for each gene at each time point relative to corresponding control are represented in boxplots (*significant fold-change compared to normoxia after ANOVA followed by pairwise t-test, adj.p-val ≤ 0.05; † adj.p-val ≤0.08).

Back to article page

Molecular Cancer

ISSN: 1476-4598