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Figure 4 | Molecular Cancer

Figure 4

From: Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor models

Figure 4

Characteristics of the HN12shSET xenograft tumors formed in nude mice. (A) Images of tumors formed from HN12shSET cells implanted in the flanks of Balb/c nude mice (n = 10). (B) The HN12shControl cells formed a solid tumor, whereas the HN12shSET tumors were similar to a large cyst and contained a yellow-white necrotic liquid that was visible when the tumors were cut. Representative images of tumors 4 weeks after cell injection are presented. (C) The volume of the tumors formed by HN12shSET cells. (D) The number of Ki67-positive tumor cells, determined as described in the Methods section. The data are reported as the means and standard deviations (*p < 0.05).

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Molecular Cancer

ISSN: 1476-4598