Figure 5From: Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor modelsHistological analysis of the HN12shSET xenograft tumors. Representative images of HN12shSET xenograft tumors sections stained with H&E. (A) The HN12shSET cells formed a poorly differentiated tumor with reduced keratin pearl formation and liquefactive necrotic areas (black arrows), along with viable tumor cells (white arrows). (B) The HN12shSET tumors showed atypical mitoses, anaplastic cells and hemorrhages. The inserts show an inflammatory infiltrate (a) and increased blood microvessel density (b). Asterisks (*) indicate microvessels.Back to article page