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Table 1 mRNA levels of 6 motility genes in the HN12shSET cells detected by real-time PCR array

From: Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor models

Gene

Fold up-and down-regulation

 

(HN12shSET/HN12shControl)

 

Up-regulated

Vimentin

2.21

MMP-9

3.26

MYH10 (Myosin, heavy chain, non-muscle)

5.77

 

Down-regulated

SRC (V-src sarcoma (Schmidt-Ruppin

−2.28

A-2) viral oncogene homolog (avian))

WASL Wiskott-Aldrich syndrome-like

−2.28

LIMK1 (LIM domain kinase 1) -

−2.73

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Molecular Cancer

ISSN: 1476-4598