Figure 3
From: SNAI1 is critical for the aggressiveness of prostate cancer cells with low E-cadherin
E-cadherin knock-down increases the expression of stemness, EMT, and bone metastasis biomarkers in PC3 cells . (A-B) Sh-PC3 or ShEC-PC3 cells were collected at similar confluency and total cell lysates were prepared and analyzed for the protein expression of E-cadherin, CD44, cleaved Notch-1, Egr-1, Vimentin, Integrin β3, N-cadherin, OB-cadherin, CXCR4, uPA, RANKL, and RunX2. Tubulin and β-actin were used as loading controls.