Table 1 Summary of IHC markers and cytogenetic abnormalities in different metastatic RCC subtypes
From: Molecular subtyping of metastatic renal cell carcinoma: implications for targeted therapy
mRCC Subtypes (n) | IHC | Cytogenetics | ||
|---|---|---|---|---|
| Â | CK7 | AMACR | 3p deletion | Trisomy 7 and/or 17 |
CCRCC (32) | 0% (0/32) | 34% (11/32) | 63%(20/32) | 0% (0/32) |
PRCC (8) | 38% (3/8) | 100% (8/8) | 0% (0/8) | 75% (6/8) |
Not classified (63) | 6% (4/63) | 63% (40/63) | 35% (22/63) | 16% (10/63) |
Total (103) | 7% (7/103) | 57% (59/103) | 41% (42/103) | 16% (16/103) |