TY - JOUR AU - Ikui, A. E. AU - Yang, C. P. AU - Matsumoto, T. AU - Horwitz, S. B. PY - 2005 DA - 2005// TI - Low concentrations of taxol cause mitotic delay followed by premature dissociation of p55CDC from Mad2 and BubR1 and abrogation of the spindle checkpoint, leading to aneuploidy JO - Cell Cycle VL - 4 UR - https://doi.org/10.4161/cc.4.10.2061 DO - 10.4161/cc.4.10.2061 ID - Ikui2005 ER - TY - JOUR AU - Yang, Z. AU - Kenny, A. E. AU - Brito, D. A. AU - Rieder, C. L. PY - 2009 DA - 2009// TI - Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachments JO - J Cell Biol VL - 186 UR - https://doi.org/10.1083/jcb.200906150 DO - 10.1083/jcb.200906150 ID - Yang2009 ER - TY - JOUR AU - Gascoigne, K. E. AU - Taylor, S. S. PY - 2008 DA - 2008// TI - Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs JO - Cancer Cell VL - 14 UR - https://doi.org/10.1016/j.ccr.2008.07.002 DO - 10.1016/j.ccr.2008.07.002 ID - Gascoigne2008 ER - TY - JOUR AU - Risinger, A. L. AU - Mooberry, S. L. PY - 2011 DA - 2011// TI - Cellular studies reveal mechanistic differences between taccalonolide A and paclitaxel JO - Cell Cycle VL - 10 UR - https://doi.org/10.4161/cc.10.13.16238 DO - 10.4161/cc.10.13.16238 ID - Risinger2011 ER - TY - JOUR AU - Schiff, P. B. AU - Horwitz, S. B. PY - 1980 DA - 1980// TI - Taxol stabilizes microtubules in mouse fibroblast cells JO - Proc Natl Acad Sci U S A VL - 77 UR - https://doi.org/10.1073/pnas.77.3.1561 DO - 10.1073/pnas.77.3.1561 ID - Schiff1980 ER - TY - JOUR AU - Orth, J. D. AU - Kohler, R. H. AU - Foijer, F. AU - Sorger, P. K. AU - Weissleder, R. AU - Mitchison, T. J. PY - 2011 DA - 2011// TI - Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics JO - Cancer Res VL - 71 UR - https://doi.org/10.1158/0008-5472.CAN-11-0412 DO - 10.1158/0008-5472.CAN-11-0412 ID - Orth2011 ER - TY - JOUR AU - Sackett, D. L. AU - Fojo, T. PY - 2011 DA - 2011// TI - Taccalonolides: a microtubule stabilizer poses a new puzzle with old pieces JO - Cell Cycle VL - 10 UR - https://doi.org/10.4161/cc.10.19.17126 DO - 10.4161/cc.10.19.17126 ID - Sackett2011 ER - TY - JOUR AU - Komlodi-Pasztor, E. AU - Sackett, D. AU - Wilkerson, J. AU - Fojo, T. PY - 2011 DA - 2011// TI - Mitosis is not a key target of microtubule agents in patient tumors JO - Nat Rev Clin Oncol VL - 8 UR - https://doi.org/10.1038/nrclinonc.2010.228 DO - 10.1038/nrclinonc.2010.228 ID - Komlodi-Pasztor2011 ER - TY - JOUR AU - Tinley, T. L. AU - Randall-Hlubek, D. A. AU - Leal, R. M. AU - Jackson, E. M. AU - Cessac, J. W. AU - Quada, J. C. AU - Hemscheidt, T. K. AU - Mooberry, S. L. PY - 2003 DA - 2003// TI - Taccalonolides E and A: Plant-derived steroids with microtubule-stabilizing activity JO - Cancer Res VL - 63 ID - Tinley2003 ER - TY - JOUR AU - Risinger, A. L. AU - Jackson, E. M. AU - Polin, L. A. AU - Helms, G. L. AU - LeBoeuf, D. A. AU - Joe, P. A. AU - Hopper-Borge, E. AU - Luduena, R. F. AU - Kruh, G. D. AU - Mooberry, S. L. PY - 2008 DA - 2008// TI - The taccalonolides: microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms JO - Cancer Res VL - 68 UR - https://doi.org/10.1158/0008-5472.CAN-08-2037 DO - 10.1158/0008-5472.CAN-08-2037 ID - Risinger2008 ER - TY - JOUR AU - Buey, R. M. AU - Barasoain, I. AU - Jackson, E. AU - Meyer, A. AU - Giannakakou, P. AU - Paterson, I. AU - Mooberry, S. AU - Andreu, J. M. AU - Diaz, J. F. PY - 2005 DA - 2005// TI - Microtubule interactions with chemically diverse stabilizing agents: thermodynamics of binding to the paclitaxel site predicts cytotoxicity JO - Chem Biol VL - 12 UR - https://doi.org/10.1016/j.chembiol.2005.09.010 DO - 10.1016/j.chembiol.2005.09.010 ID - Buey2005 ER - TY - JOUR AU - Li, J. AU - Risinger, A. L. AU - Peng, J. AU - Chen, Z. AU - Hu, L. AU - Mooberry, S. L. PY - 2011 DA - 2011// TI - Potent taccalonolides, AF and AJ, inform significant structure-activity relationships and tubulin as the binding site of these microtubule stabilizers JO - J Am Chem Soc VL - 133 UR - https://doi.org/10.1021/ja209045k DO - 10.1021/ja209045k ID - Li2011 ER - TY - JOUR AU - Risinger, A. L. AU - Li, J. AU - Bennett, M. J. AU - Rohena, C. C. AU - Peng, J. AU - Schriemer, D. C. AU - Mooberry, S. L. PY - 2013 DA - 2013// TI - Taccalonolide binding to tubulin imparts microtubule stability and potent in vivo activity JO - Cancer Res VL - 73 UR - https://doi.org/10.1158/0008-5472.CAN-13-1346 DO - 10.1158/0008-5472.CAN-13-1346 ID - Risinger2013 ER - TY - JOUR AU - Rohena, C. C. AU - Peng, J. AU - Johnson, T. A. AU - Crews, P. AU - Mooberry, S. L. PY - 2013 DA - 2013// TI - Chemically diverse microtubule stabilizing agents initiate distinct mitotic defects and dysregulated expression of key mitotic kinases JO - Biochem Pharmacol VL - 85 UR - https://doi.org/10.1016/j.bcp.2013.01.030 DO - 10.1016/j.bcp.2013.01.030 ID - Rohena2013 ER - TY - JOUR AU - Hornick, J. E. AU - Bader, J. R. AU - Tribble, E. K. AU - Trimble, K. AU - Breunig, J. S. AU - Halpin, E. S. AU - Vaughan, K. T. AU - Hinchcliffe, E. H. PY - 2008 DA - 2008// TI - Live-cell analysis of mitotic spindle formation in taxol-treated cells JO - Cell Motil Cytoskeleton VL - 65 UR - https://doi.org/10.1002/cm.20283 DO - 10.1002/cm.20283 ID - Hornick2008 ER - TY - JOUR AU - Gaglio, T. AU - Saredi, A. AU - Compton, D. A. PY - 1995 DA - 1995// TI - NuMA is required for the organization of microtubules into aster-like mitotic arrays JO - J Cell Biol VL - 131 UR - https://doi.org/10.1083/jcb.131.3.693 DO - 10.1083/jcb.131.3.693 ID - Gaglio1995 ER - TY - JOUR AU - Quintyne, N. J. AU - Reing, J. E. AU - Hoffelder, D. R. AU - Gollin, S. M. AU - Saunders, W. S. PY - 2005 DA - 2005// TI - Spindle multipolarity is prevented by centrosomal clustering JO - Science VL - 307 UR - https://doi.org/10.1126/science.1104905 DO - 10.1126/science.1104905 ID - Quintyne2005 ER - TY - JOUR AU - Dhamodharan, R. AU - Jordan, M. A. AU - Thrower, D. AU - Wilson, L. AU - Wadsworth, P. PY - 1995 DA - 1995// TI - Vinblastine suppresses dynamics of individual microtubules in living interphase cells JO - Mol Biol Cell VL - 6 UR - https://doi.org/10.1091/mbc.6.9.1215 DO - 10.1091/mbc.6.9.1215 ID - Dhamodharan1995 ER - TY - JOUR AU - Jordan, M. A. AU - Thrower, D. AU - Wilson, L. PY - 1991 DA - 1991// TI - Mechanism of inhibition of cell proliferation by Vinca alkaloids JO - Cancer Res VL - 51 ID - Jordan1991 ER - TY - JOUR AU - Jordan, M. A. AU - Toso, R. J. AU - Thrower, D. AU - Wilson, L. PY - 1993 DA - 1993// TI - Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations JO - Proc Natl Acad Sci U S A VL - 90 UR - https://doi.org/10.1073/pnas.90.20.9552 DO - 10.1073/pnas.90.20.9552 ID - Jordan1993 ER - TY - JOUR AU - Jordan, M. A. AU - Wendell, K. AU - Gardiner, S. AU - Derry, W. B. AU - Copp, H. AU - Wilson, L. PY - 1996 DA - 1996// TI - Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death JO - Cancer Res VL - 56 ID - Jordan1996 ER - TY - JOUR AU - Jordan, M. A. AU - Wilson, L. PY - 1998 DA - 1998// TI - Use of drugs to study role of microtubule assembly dynamics in living cells JO - Methods Enzymol VL - 298 UR - https://doi.org/10.1016/S0076-6879(98)98024-7 DO - 10.1016/S0076-6879(98)98024-7 ID - Jordan1998 ER - TY - JOUR AU - Risinger, A. L. AU - Natarajan, M. AU - Thomas, C. R. AU - Mooberry, S. L. PY - 2011 DA - 2011// TI - The taccalonolides, novel microtubule stabilizers, and gamma-radiation have additive effects on cellular viability JO - Cancer Lett VL - 307 UR - https://doi.org/10.1016/j.canlet.2011.03.022 DO - 10.1016/j.canlet.2011.03.022 ID - Risinger2011 ER - TY - JOUR AU - Kamath, K. AU - Jordan, M. A. PY - 2003 DA - 2003// TI - Suppression of microtubule dynamics by epothilone B is associated with mitotic arrest JO - Cancer Res VL - 63 ID - Kamath2003 ER - TY - JOUR AU - Yenjerla, M. AU - Lopus, M. AU - Wilson, L. PY - 2010 DA - 2010// TI - Analysis of dynamic instability of steady-state microtubules in vitro by video-enhanced differential interference contrast microscopy with an appendix by Emin Oroudjev JO - Methods Cell Biol VL - 95 UR - https://doi.org/10.1016/S0091-679X(10)95011-5 DO - 10.1016/S0091-679X(10)95011-5 ID - Yenjerla2010 ER - TY - JOUR AU - Lopus, M. AU - Manatschal, C. AU - Buey, R. M. AU - Bjelic, S. AU - Miller, H. P. AU - Steinmetz, M. O. AU - Wilson, L. PY - 2012 DA - 2012// TI - Cooperative stabilization of microtubule dynamics by EB1 and CLIP-170 involves displacement of stably bound P(i) at microtubule ends JO - Biochemistry VL - 51 UR - https://doi.org/10.1021/bi300038t DO - 10.1021/bi300038t ID - Lopus2012 ER - TY - JOUR AU - Dave, R. H. AU - Saengsawang, W. AU - Lopus, M. AU - Dave, S. AU - Wilson, L. AU - Rasenick, M. M. PY - 2011 DA - 2011// TI - A molecular and structural mechanism for G protein-mediated microtubule destabilization JO - J Biol Chem VL - 286 UR - https://doi.org/10.1074/jbc.M110.196436 DO - 10.1074/jbc.M110.196436 ID - Dave2011 ER - TY - JOUR AU - Oroudjev, E. AU - Lopus, M. AU - Wilson, L. AU - Audette, C. AU - Provenzano, C. AU - Erickson, H. AU - Kovtun, Y. AU - Chari, R. AU - Jordan, M. A. PY - 2010 DA - 2010// TI - Maytansinoid-antibody conjugates induce mitotic arrest by suppressing microtubule dynamic instability JO - Mol Cancer Ther VL - 9 UR - https://doi.org/10.1158/1535-7163.MCT-10-0645 DO - 10.1158/1535-7163.MCT-10-0645 ID - Oroudjev2010 ER - TY - JOUR AU - Tinley, T. L. AU - Leal, R. M. AU - Randall-Hlubek, D. A. AU - Cessac, J. W. AU - Wilkens, L. R. AU - Rao, P. N. AU - Mooberry, S. L. PY - 2003 DA - 2003// TI - Novel 2-methoxyestradiol analogues with antitumor activity JO - Cancer Res VL - 63 ID - Tinley2003 ER -