Figure 1

Correlation between N-RAS mutation status and survival probability in melanoma patients. Kaplan-Meier survival curves demonstrating the overall survival from time of diagnosis of stage IV disease. Panel A shows survival curves for all three patient groups, whereas panel B shows the patients with N-RAS mutations compared to B-RAF and WT combined. Patients with N-RAS mutations had a trend towards shorter median survival when compared to the non N-RAS WT counterparts (p = 0.12).