Skip to main content

Table 1 Immunohistochemical analysis of AMPK-β1 on an ovarian cancer tissue array (OVC1021, Pantomics, Inc.)

From: Reduced expression of AMPK-β1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer

  

AMPKβ1 expression [fold change]

 

Characteristics

Total

≤ 3-fold

>3-fold

P

All cases

97

57 (58.8)

40 (41.2)

 

Stage

    

 Early (1 + 2)

73

37 (50.7)

36 (49.3)

 

 Late (3)

24

20 (83.3)

4 (16.7)

0.008*

Grade

    

 Low

50

23 (46.0)

27 (54.0)

 

 High

46

33 (71.7)

13 (28.3)

0.013*

Metastasis

    

 No

73

37 (50.7)

36 (49.3)

 

 Yes

24

20 (83.3)

4 (16.7)

0.008*

  1. Clinicopathological analysis showed that down-regulated AMPK-β1 (≤3-fold) was associated with late stage (P = 0.008) and high-grade (P = 0.013) cancer and the presence of metastasis (P = 0.008). P, p-value. *, statistical significance.
Back to article page

Molecular Cancer

ISSN: 1476-4598