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Figure 1 | Molecular Cancer

Figure 1

From: NF-kappa B mediated Up-regulation of CCCTC-binding factor in pediatric acute lymphoblastic leukemia

Figure 1

CTCF levels are dramatically up-regulated in pediatric ALL cases. (A) A heat map of CTCF mRNA levels (blue box). The fold change in expression compared with the control is indicated by the color intensity, with red representing up-regulation. Refer to the additional file 4 of reference [16] for more details. HD, hyperdiploid>50 chromosomes. (B) CTCF mRNA levels were measured by qRT-PCR in paired cDNA samples from 10 ALL patients (n = 20). Each paired sample refers to two samples from the same patient at the time of ND and CR. CTCF mRNA levels were increased in the ND samples compared with the CR samples (fold change 2.05, p = 0.000, paired samples t-test). Each assay was repeated three times. ND, newly diagnosed. CR, complete remission.

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