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Figure 5 | Molecular Cancer

Figure 5

From: Hypoxia differentially regulated CXCR4 and CXCR7 signaling in colon cancer

Figure 5

Activation of Akt and Erk oncogenic pathways by stimulation of CXCR4/CXCL12 axis in SW480 cell line. Effect of CXCL12 stimulation on Akt and Erk oncogenic pathways. SW480 cells were stimulated with CXCL12 at concentration of 0.5 nM. The cells cultivated either in normoxia or in hypoxia (1%O2) and previously starved for 4 h in a serum-free medium before adding CXCL12, were evaluated for protein kinase phosphorylation.

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