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Figure 5 | Molecular Cancer

Figure 5

From: Downregulation of BRAF activated non-coding RNA is associated with poor prognosis for non-small cell lung cancer and promotes metastasis by affecting epithelial-mesenchymal transition

Figure 5

Effects of BANCR overexpression on tumor metastasis in vivo . (A) BANCR expression levels were determined by qPCR following the treatment of A549 cells with si-BANCR. (B) Transwell assays were conducted to determine the migratory and invasive abilities of si-BANCR-transfected A549 cells. Analysis of an experimental metastasis animal model was performed by injecting BANCR-overexpressing SPC-A1 cells into nude mice. (C) Lungs from mice in each experimental group, with the numbers of tumor nodules on lung surfaces were shown. (D) Visualization of the entire lung, and HE-stained lung sections. **P < 0.01.

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