Figure 6

BANCR overexpression suppresses NSCLC cell invasion and metastasis by affecting EMT. (A, B) Analysis of E-cadherin, N-cadherin, Vimentin, MMP-2, MMP-9, SNAIL1, SNAIL2, TWIST and SIP1 expression in A549 cells treated with pCDNA-BANCR. (C,D) Analysis of E-cadherin and Vimentin expression in A549 cells treated with pCDNA-BANCR by western blot and immunofluorescence. All experiments were performed in triplicate with three technical replicates. *P < 0.05 , **P < 0.01.