Figure 2
From: Autophagic flux determines cell death and survival in response to Apo2L/TRAIL (dulanermin)
Apo2L/TRAIL treatment (TR) induces autophagy. (A) Clonogenic survival assay following TR at the indicated doses (*p < 0.001). (B) Electron microscopic analyses of autophagic structures at the indicated time following TR ± CQ. Scale bar, 500 nm (C) Quantitative analysis of the autophagic area normalized to the cytoplasmic area following TR ± CQ (*p < 0.001, **p < 0.05). Data represent means ± SEM (>3 different fields per sample).