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Figure 4 | Molecular Cancer

Figure 4

From: Divergent effects of muscarinic receptor subtype gene ablation on murine colon tumorigenesis reveals association of M3R and zinc finger protein 277 expression in colon neoplasia

Figure 4

Analyses of gene expression in tumors from WT and Chrm3-/-mice. A: Heat map displaying expression pattern of the 28 genes with the largest changes in expression when comparing tumors from Chrm3-/- relative to tumors from WT mice. Rows represent genes and columns represent samples. Color intensity denotes the standardized ratio between each value and the average expression of each gene across all samples. Red pixels indicate increased abundance and green pixels decreased abundance of each transcript in the indicated sample. N = 3 mice/ genotype. B: Comparison of changes in murine gene expression levels in tumors from Chrm3-/- mice relative to tumors from WT mice quantified by real time RT-PCR (qPCR). WT, wild-type.

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Molecular Cancer

ISSN: 1476-4598