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Figure 6 | Molecular Cancer

Figure 6

From: Divergent effects of muscarinic receptor subtype gene ablation on murine colon tumorigenesis reveals association of M3R and zinc finger protein 277 expression in colon neoplasia

Figure 6

M3R and ZNF277 gene and protein expression in human colon cancer compared to adjacent normal colon. A: CHRM3 and ZNF277 mRNA levels in 12 sets of colon cancer and adjacent normal colon obtained from the same patients. mRNA levels were first normalized to expression of β2-microglobulin and then ranked by increasing levels of CHRM3 expression. B: Representative images show immunohistochemical staining with anti-ZNF277 and anti-M3R antibodies on human colon cancer and adjacent normal colon epithelial tissue. Size bars = 100 micrometers. C: Graph shows quantification of ZNF277 and M3R staining in cancer compared to normal colon. Data shown represent mean ± S.E. of 23 sets of colon cancer and adjacent normal colon tissues.

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Molecular Cancer

ISSN: 1476-4598