Figure 1
From: Critical role of histone demethylase RBP2 in human gastric cancer angiogenesis
Association of RBP2 overexpression and increased VEGF expression in human gastric cancer. QRT-PCR analyses of (A) RBP2 mRNA and (B) VEGF mRNA in normal and cancerous human gastric tissues. *P < 0.05. (C) Correlation of RBP2 and VEGF levels in human gastric cancer tissues after standardization with matched normal tissues. **P < 0.01. (D) Immunohistochemical staining of expression of RBP2, VEGF, CD31, CD34 and Ki67 in human normal (left panel) and cancerous (right panel) gastric tissues. Representative images are shown. (E) Percentage positive cells by immunohistochemistry for RBP2, VEGF and Ki67 in human normal and cancerous gastric tissues. **P < 0.01. (F) Percentage positive area by immunohistochemistry for CD31 and CD34 in human normal and cancerous gastric tissues. **P < 0.01. Data are mean ± SEM of 3 independent experiments.