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Figure 4 | Molecular Cancer

Figure 4

From: Targeting gallbladder cancer: oncolytic virotherapy with myxoma virus is enhanced by rapamycin in vitro and further improved by hyaluronan in vivo

Figure 4

Gallbladder cancer cell lines express MMP-9 and CD44 mRNA, and hyaluronan treatment increases MMP-9 mRNA expression. A, B. MMP-9 and CD44 mRNA expression in GBC-SD at different HA concentrations (*, P < 0.05). C. D. Gelatin zymogram of MMP-9 and pro-MMP-9 from supernatants and membrane extracts of GBC-SD and their relative activity levels by densitometric scans (*, compared with HA group, p< 0.05). E. Crystal violet staining of GBC-SD and SGC-996 invasive cells on the outer surface of the upper chambers following the addition of HA. F. Percentage of positive cells per microscope field.

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Molecular Cancer

ISSN: 1476-4598