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Figure 1 | Molecular Cancer

Figure 1

From: TFAP2B overexpression contributes to tumor growth and a poor prognosis of human lung adenocarcinoma through modulation of ERK and VEGF/PEDF signaling

Figure 1

TFAP2B protein is highly expressed in lung cancer cells and tumor tissues and associated with a poor prognosis. The expression of TFAP2B proteins in various lung cancer cell lines and human normal cells (A), as well as in tumor tissues (B) were analyzed by Western blotting and immunohistochemical analyses using a human TFAP2B antibody. Original magnification, 200×. (C) Immunohistochemical staining of a tissue microarray with lung adenocarcinoma sections. The representative areas of lung adenocarcinomas stained using a monoclonal anti-human TFAP2B antibody and scored as 0, 1+, and 2+. A strong positive staining was observed in cancer cells, whereas the adjacent area staining was weak. Original magnification, 200×. (D) TFAP2B overexpression correlates with a poor prognosis in patients with lung adenocarcinomas. Kaplan-Meier curves of overall survival in all (n = 147) patients.

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Molecular Cancer

ISSN: 1476-4598