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Figure 3 | Molecular Cancer

Figure 3

From: A dedicated microarray for in-depth analysis of pre-mRNA splicing events: application to the study of genes involved in the response to targeted anticancer therapies

Figure 3

Effects of SRSF2 overexpression on the response to gefitinib in H358 lung adenocarcinoma cells. The H358/Tet-On/SRSF2 inducible H358 clone was treated or not for 24 hours with increasing concentrations of gefitinib as indicated, in the presence (+) or absence (-) of 1 μg/mL doxycyclin. Western blot analysis was performed using the indicated antibodies. Apoptosis was analyzed by the detection of PARP or caspase-3 activation. Tubulin was used as a loading control.

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Molecular Cancer

ISSN: 1476-4598