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Figure 3 | Molecular Cancer

Figure 3

From: Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer

Figure 3

The effect of HOTAIR on gastric cancer cell apoptosis, migration and invasion in vitro . BGC-823 cells were transfected with si-HOTAIR or si-NC, and SGC-7901 cells were transfected with pCDNA/HOTAIR vector or empty vector control. (A) Hoechst staining assay of cell apoptosis; the percentage of Hoechst-positive nuclei per optical field (at least 50 fields) was determined. (B) The apoptotic rates of cells were detected by flow cytometry. UL, necrotic cells; UR, terminal apoptotic cells; LR, early apoptotic cells. (C and D) Transwell assays were performed to investigate changes in cell migration and invasiveness. *P < 0.05 and **P < 0.01.

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Molecular Cancer

ISSN: 1476-4598