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Table 1 Correlation of the expression of HOTAIR with clinicopathologic features

From: Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer

Clinicopathologic features

n (%)

Relative expression of HOTAIRa

P-valueb

Gender

  

P = 0.62

Male

50 (64)

12.21 (0.97-17.53)

 

Female

28 (36)

15.01 (7.34 -19.52)

 

Site of tumor

  

P = 0.910

Distal third

18 (23)

9.1 (1.37-14.12)

 

Middle third

20 (26)

7.96 (2.55-9.72)

 

Proximal stomach

40 (51)

7.76 (1.24-13.58)

 

Differentiation

  

P = 0.045

Poor

56 (72)

15.6 (6.25-20.36)

 

High/moderate

22 (28)

8.1 (0.98-11.14)

 

Lymph node Metastasis

  

P = 0.005

N0

10 (13)

1.14 (0.75-1.42)

 

N1

11 (14)

3.44 (1.15-4.85)

 

N2

29 (37)

11.99 (7.15-14.77)

 

N3

28 (36)

32.58 (7.34-36.27)

 

Metastatic disease

  

P = 0.029

M0

64 (82)

9.35 (2.53-33.64)

 

M1

14 fig

28.82 (16.39-39.39)

 
  1. aMedian of relative expression, with 25th-75th percentile in parentheses. bP < 0.05 was considered significant (Mann–Whitney U test between 2 groups and Kruskall-Wallis test for 3 groups).
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Molecular Cancer

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