Figure 6From: Melanoma cells influence the differentiation pattern of human epidermal keratinocytes Melanoma cell activity is in addition to other factors dependent on the activity of tumor infiltrating inflammatory cells and fibroblasts. The melanoma cells are able to influence the differentiation pattern of keratinocytes by production of FGF-2, VEGF-A, IL-8, and CXCL-1. The reciprocal activity of keratinocytes to melanoma cells needs further research.Back to article page