Figure 1
From: NF-κB induces miR-148a to sustain TGF-β/Smad signaling activation in glioblastoma
Restoration of QKI inhibits glioma tumorigenesis. Western blotting (WB) of QKI in (A) three normal brain tissues and 12 glioma tissues, and (B) NHAs and seven glioblastoma cell lines. β-Actin was used as the loading control. (C) Kaplan–Meier analysis of QKI expression in survival of patients with glioblastoma (P = 0.002, log-rank test; n = 167). (D) QKI expression was inversely associated with VEGF and MMP9 expression in 167 clinical glioma specimens. Figures are visualizations of two representative cases and percentages of samples with low or high QKI expression relative to VEGF or MMP9 levels.