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Table 2 Performance of SCCA, POU3F3 , and both SCCA and POU3F3 in the differential diagnosis ESCC from healthy participants

From: Identification of the long non-coding RNA POU3F3 in plasma as a novel biomarker for diagnosis of esophageal squamous cell carcinoma

 

Sensitivity

Specificity

Accuracy

Youden index

True positive

True negative

False-positive

False-negative

SCCA

59.2%

93.5%

74.8%

52.7%

87

115

8

60

POU3F3

72.8%

89.4%

80.3%

62.2%

107

110

13

40

SCCA + POU3F3

85.7%

81.4%

83.7%

67.1%

126

100

23

21

  1. Abbreviations: SCCA squamous cell carcinoma antigen.
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Molecular Cancer

ISSN: 1476-4598