Gene | Reference | Normal | PanIN1A | PanIN1B | PanIN2 | PanIN3 | Carcinoma |
---|---|---|---|---|---|---|---|
K-RAS | [6] | 0% | 38% | 44% | Â | 87% | Â |
 | [36] | 3% | 30% | 31% | 73% |  |  |
 |  |  |  |  |  |  | ~90% |
INK4a | [19] | 0% | 30% | 27% | 55% | 71% | 100% |
 | [14] |  | 33% |  |  |  | 40% |
TP53 | [37] | 0% | Â | Â | Â | 12% | 40% |
 | [35] | 0% |  | 35% |  | 36% | 40% |
 | [36] | 0% | 0% | 0% | 9,1% |  | 87% |
 | [9] | 0% | 0% | 0% | 20% | 57% | 47% |
DPC4/Smad4 | [47] | Â | 0% | 0% | 0% | 31% | 55% |
 | [9] | 0% | 0% | 0% | 0% | 33% | 66% |